tert-butyl (3-formyl-4-hydroxyphenyl)carbamate - Names and Identifiers
tert-butyl (3-formyl-4-hydroxyphenyl)carbamate - Introduction
tert-butyl (3-formyl-4-hydroxyphenyl)carbamate is an organic compound, also known as TBFC. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow crystal or crystalline powder
-Molecular formula: C13H17NO4
-Molecular weight: 251.28g/mol
-melting point: 95-99 ℃
-Solubility: TBFC is soluble in non-polar solvents such as ethanol, dimethylformamide and dichloromethane
-Stability: relatively stable under normal storage conditions
Use:
TBFC is often used as a starting material or intermediate in organic synthesis. It has important applications in the synthesis of new drugs, pesticides and pigments and other chemicals. TBFC is also used to synthesize organic macromolecules with biological activity.
Preparation Method:
TBFC can be synthesized by the following steps:
1. 3-hydroxy p-cresol reacts with di-tert-butyl carbonate to produce p-cresol tert-butyrate.
2. p-cresol tert-butyrate is converted to p-cresol tert-butyl carbamate by amination reaction.
3. react p-cresol tert-butyl carbamate with formaldehyde to form tert-butyl (3-formyl-4-hydroxyphenyl)carbamate.
Safety Information:
TBFC has limited safety data, so safety operating procedures need to be followed. It may be irritating to the eyes and skin, so contact should be avoided during use. Wear appropriate protective equipment such as gloves and goggles when using. Keep it away from ignition and oxidizing agents when handling or storing. If an accident occurs, the compound should be disposed of or recovered in a well-ventilated area. It is best to operate and handle the substance under the guidance of an experienced chemical professional.
Last Update：2024-04-09 21:32:44